| 1948 | ・RIKEN reorganized into Kagaku-Kenkyusho (the first president, Dr. Yoshio Nishina) ・Penicillin production started |
| 1950 | ・Streptomycin production started |
| 1952 | ・Kagaku-Kenkyusho renamed Kaken Chemicals |
| 1962 | ・Kaken Chemicals listed on the First Section of the Tokyo Stock Exchange ・Shizuoka Factory opened |
| 1966 | ・Shiga Factory opened |
| 1972 | ・Brufen launched |
| 1975 | ・Kyoto Research Laboratories completed in Yamashina, Kyoto |
| 1978 | ・Eustin (Salinomycin) launched |
| 1982 | ・Kaken Chemicals merged with Kakenyaku-Kako to form KAKEN PHARMACEUTICAL |
| 1984 | ・Seven E-P launched |
| 1987 | ・Artz launched ・Empynase-PD launched |
| 1988 | ・Fiblast in-licensed from California Biotechnology (Scios) ・Adofeed launched |
| 1989 | ・Komagome redevelopment plan started ・Ebrantil launched |
| 1991 | ・Head office moved to Urayasu in Chiba |
| 1992 | ・Mentax launched ・Mentax out-licensed to Penederm, (renamed to Bertek recently) ・Procylin launched ・Ropion launched |
| 1993 | ・Artz Dispo launched |
| 1995 | ・Pronase-MS launched ・Uroston launched
・Cytotec launched |
| 1996 | ・Mentax approved by U.S. Food and Drug Administration |
| 1997 | ・Seprafilm marketing agreement made with Genzyme Corp. |
| 1998 | ・Bunkyo Green Court completed ・50th Anniversary celebrated
・Pentoxazon launched ・Seprafilm launched |
| 1999 | ・Lipantil launched ・Mr. Inui named for the president |
| 2000 | ・Shiga Factory closed |
| 2001 | ・Mirol launched ・Fiblast Spray launched
・ISO14001 obtained in Shizuoka site |
| 2002 | ・Mentax launched as OTC in U.S. |
| 2003 | ・Drug Information Service Office opened |
| 2004 | ・Mentax Spray launched |
| 2005 | ・Lipidil launched ・bFGF-the rights to develop, manufacture and sell on a world basis obtained |
| 2006 | ・Licensing Agreement for Antifungal compound “KP-103” in North America and Europe |
| 2007 | ・Licensing Agreement for Dental Applications of bFGF in North America and Europe
・Licensing Agreement for Anti-alpha-9 integrin antibodies on a world basis ・Berasus lanched |
| 2009 | ・License Agreement for bFGF in Wound Healing Applications in Europe and North America |
