History

1948 Riken reorganized into Kagaku-Kenkyusho
Launched "Penicillin Kaken"
1950 Launched "Streptomycin Kaken"
1952 Kagaku-Kenkyusho renamed Kaken Chemicals
1953 Launched "Athletan" (anti-trichophyton product)
1962 Kaken Chemicals listed on the First Section of the Tokyo Stock Exchange
1963 Completed Shizuoka Factory
1965 Received the 11th Okochi Memorial Prize
1971 Received the 17th Okochi Memorial Prize
1982 Kaken Chemicals merged with Kakenyaku-Kako to form KAKEN PHARMACEUTICAL CO., LTD.
1987 Launched "Artz" (anti-osteoarthritis agent)
1988 Kaken Pharma Co., Ltd. established
Launched "Adofeed"
1989 Launched "Ebrantil" (anti-dysuria agent)
1992 Launched "Procylin"
Launched "Mentax"
1993 Launched "Artz Dispo" (anti-osteoarthritis agent)
1994 Received the 40th Okochi Memorial Prize
1995 Received the 41st Okochi Memorial Prize
1996 Mentax approved by U.S. Food and Drug Administration
1998 Completed Bunkyo Green Court
Launched "Seprafilm" (post-operative adhesion barrier)
2000 Won the fiscal 2000 3Rs (Reduce, Reuse and Recycle) Promotion Merit Award and the Minister of Health and Welfare Award
2001 ISO14001 obtained in Shizuoka site
Launched "Fiblast Spray" (wound-healing agent)
2004 Launched "Mentax Spray"
2005 Obtained the rights to develop, manufacture and sell bFGF globally
2006 Out-licensed antifungal compound “KP-103” in North America and Europe
2007 Launched "Berasus"
2011 Launched "Lipidil"
2014 Launched "Clenafin" (onychomycosis treatment)
2015 In-licensed "BBI-4000" in Japan and certain other Asian countries
2016 Acquired exclusive rights to develop and distribute "NexoBrid" in Japan
Out-licensed "Clenafin" in South Korea
Launched "Regroth dental kit" (periodontal regenerative agent)
2017 Launched collaborative research with Numab Therapeutics AG to develop a new antibody drug
Out-licensed "Clenafin" in Taiwan
2018 Launched "Hernicore" (lumbar disc herniation treatment)
Out-licensed "Clenafin" in Hong Kong and Macau
2019 Acquired exclusive rights to distribute "Lenabasum" (systemic sclerosis and dermatomyositis treatment) in Japan
Out-licensed "Clenafin" in China
Acquired exclusive rights to develop and distribute "Ivermectin lotion 0.5% (head lice treatment) in Japan
2020 Launched "Ecclock" Gel 5% (primary axillary hyperhidrosis treatment)
2021 Out-licensed "Clenafin" in Europe
Acquired ARTham Therapeutics Inc. and made it a subsidiary
2023 ・Acquired exclusive rights to develop and distribute "Seladelpar" (Primary biliary cholangitis treatment) in Japan
・Acquired exclusive rights to develop and distribute "Tildacerfont" (Congenital adrenal hyperplasia treatment) in Japan
2024 ・Acquired marketing authorization for “Merislon” (dizziness and equilibrium disorder treatment) and "Mional"(muscle relaxant) from Eisai Co., Ltd.
・Concluded an agreement for the transfer of intellectual property rights and a marketing alliance option for "NM26" (atopic dermatitis treatment).
・Acquired exclusive domestic marketing rights for "Silk Elastin Wound Sheet" (wound dressing).
・Entered into a  joint research agreement for "ND081" (inflammatory bowel disease treatment).
・Acquired Aadi Subsidiary, Inc. (now Aadi Bioscience, Inc.) and its product "FYARRO" (acquisition completed in March 2025).
・Signed a license agreement for a STAT6 inhibitor (oral treatment for Type 2 inflammatory diseases such as atopic dermatitis and asthma).
・Acquired exclusive domestic rights for development, manufacturing, and marketing of "ESK-001" (TYK2 inhibitor for psoriasis vulgaris, etc.).
・Obtained marketing authorization for “Clenafin” in Italy.
2025 ・Entered into a license agreement for "gMSC1" (allogeneic synovial mesenchymal stem cell-derived 3D artificial tissue).
・Acquired development and marketing rights in Japan for "navenibart“ a long-term prophylactic treatment for hereditary angioedema (HAE).
・Launched the Authorized Generic (AG) of “Clenafin“.
・Received both the "Licensing Deal of the Year" and "Pharma Company of the Year" at the Citeline Japan Awards 2025.
・Commenced co-development for "NM81“(formerly ND081), an inflammatory bowel disease treatment.
・Launched “ECCLOCK” in South Korea.
・In-licensed and launched "EKTERLY" (an oral plasma kallikrein inhibitor for the treatment of acute attacks of HAE) .
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